Home' Spa and Clinic : Volume 63 October 2015 Contents DA VINCI AND GROWTH FACTOR 6
"Growth factors are nothing more than shapes," says Stephanie
Sherlock, CEO of Architects of Skin.
"The body produces these shapes and is found in our plasma. It
is collected for both PRP and Factor4 procedures.
"With our technology we are applying growth factors directly to
the skin, just like PRP and Factor4, but we do not need to take blood.
"The scientists behind Da Vinci [skin rejuvenation] and Factor G6
[hair regrowth] have recreated the body's own growth factors by making
the identical shape of each growth factor out of bacteria-derived protein.
"Autologous growth factor treatments do not differentiate
between or filter growth factors. They collect them all.
"Some growth factors can generate new skin cells and hair cells
and other growth factors can do the opposite.
"Da Vinci and Factor G6 are two formulations with very specific
growth factors that either grow skin or grow hair.
"They only formulate the growth factors they want and keep out
those that generate the opposite effect.
"Blood-derived GF treatments can be painful because the serum
injected contains RBC, which sets up an inflammatory (pain,
redness) response. Therefore patients are often sedated or local
anaesthetic is applied.
"So there is less or no pain with our procedures, which are
performed via microneedling, as there is no inflammation caused
by RBC. Therefore also less downtime.
"The treatments are less expensive as there is no blood taking/
"In more than 500,000 cases worldwide there are no known side
"While the professional treatments involve micro-needling to
deliver Factor G6 and Da Vinci 21, the take-home Da Vinci 10 skin
and Factor G6 hair serum are both retail products and do not need
microneedling to deliver them.
"We certainly conduct significant training with all our clients to
ensure they are treating the patient safely and effectively. We also
offer ongoing support."
Factor4 is a relatively new autologous entry to the Australian
"The way Factor4 is processed is very different from PRP," says
Shaun Baldwin, CEO of its distributor, Klinic Solutions.
"It is an Autologous Conditioned Serum. There are no cells in
the Factor4 serum. It produces a concentration of the body's own
growth factors at a level four times that of blood. Hence the name.
"But it also elevates the anti-inflammatory cytokine IL-1Ra.
It is this cytokine that creates an environment to allow GFs to do
their work. We have injected into tissue, so this creates an effect.
The IL-1Ra soothes the inflammation.
"It was originally developed for soft tissue injuries and to fight
osteo-arthritis. Clinics that are staffed by doctors with an interest in
treating this type of problem can help their patients on many levels.
"There are now 37 practices in Australia and New Zealand
Shaun says its primary applications and benefits are preventative
and anti-ageing; for skin on the face, neck, décolletage and the
backs of the hands, to reduce crepiness, enlarged pores, fine lines
and wrinkles, help correct scars and stretch marks, and also address
dark circles under the eyes.
He says it is suitable for all skin types. The procedure involves
taking a patient's blood in technologically advanced tubing,
according to cosmetic physician Dr Christopher Leat, of the Gold
Coast's Envisage clinic.
"The drawn blood is then incubated for between six and nine
hours, exposing it to pyrogenic-free surfaces. This elicits a vigorous
and rapid increase in the synthesis of growth factors.
"Following centrifugation (the blood is "spun" to separate
its components), serum extraction and filtration, the serum is
portioned and stored in a freezer at -18°C."
"Because of the incubation period, the serum extracted is more
GF-rich than if re-injected into a patient immediately."
Factor4 and PRP can also be micro-needled rather than injected
into the skin by appropriately trained practitioners.
These subjects were treated at weekly intervals over thee months at Hair Free clinics with Growth Factors G6 applied with the Eclipse Micropen.
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